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What is Lorazepam?
Lorazepam (brand name Ativan) is a benzodiazepine that enhances the calming effects of gamma-aminobutyric acid (GABA) in the brain, helping reduce anxiety, promote sedation, and prevent seizures. It is widely prescribed for generalized anxiety disorder and short-term relief of anxiety symptoms.
Lorazepam Dosage Forms and Strengths
| Form | Strength Options (mg) | Notes |
|---|---|---|
| Oral Tablets | 0.5 mg, 1 mg, 2 mg | Commonly prescribed for anxiety and insomnia |
| Oral Solution | Varying concentrations | For patients with swallowing difficulties |
| Injection | 2 mg per mL (IV/IM use) | Used primarily in hospitals for seizure control |
Lorazepam Recommended Dosage Guidelines
| Condition | Dosage Range | Notes |
|---|---|---|
| Anxiety | 2 to 6 mg daily, divided into 2-3 doses | Adjusted by healthcare provider based on therapeutic response |
| Insomnia | 1 to 4 mg at bedtime | Low doses effective; taken once daily |
| Seizure Management | IV/IM doses of 4 mg initially, repeat as needed | Used in acute settings under medical supervision |
| Elderly Patients | Start with 0.5 mg to reduce risk of side effects | Increased sensitivity; dose adjustments necessary |
Safety and Side Effects Of Lorazepam
| Side Effect | Details |
|---|---|
| Sedation | Common; avoid activities requiring alertness |
| Dizziness | Potential fall risk, especially in elderly |
| Cognitive Impairment | Possible confusion or memory issues |
| Dependence and Withdrawal | Use for short durations to minimize risk of addiction |
| Respiratory Depression | Rare but serious with concomitant CNS depressants |
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